Report Summary

In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa

Study Summary

Overall Study Design 
Cas9gRNA vector design gRNAs were cloned into px330 vector via BbsI restriction enzyme sites upstream of 
the scaffold gRNA sequence and the mCherry reporter was cloned downstream of the Cas9 transcript which 
was under constitutive expression by cytomegalovirus promoter 
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