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Testing Services


The NGVB provides a number of tests to assist eligible investigators with meeting FDA requirements for clinical gene therapy.


Testing

  • Replication Competent Virus Testing. The NGVB offers biologic based assays for virus testing with a focus on testing for retroviral and lentiviral vectors.
  • PCR Testing. Quantitative PCR assays for vector copy number and viral detection are available, including testing for the VSV-G, GALV, and RD114 envelope DNA.
  • Insertion Site Analysis. PCR, next-generation sequencing, and bioinformatics analysis are available to eligible investigators
  • Pert Assay. Product Enhanced Reverse Transcriptase (PERT) Assay. PERT is a quantitative PCR based assay that uses the test material as a source of reverse transcriptase to convert a known quantity of mRNA into a DNA transcript.
  • p24 ELISA. Determining the concentration of p24 in a test article can serve to estimate the number of lentiviral vector particles or HIV-1 virions.

Request Testing Services

For questions please contact the NGVB Manager:

NGVB Manager
317-274-4519
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