The NGVB provides testing for a variety of viral sequences, with a focus on viral envelopes. Assays comply with Good Manufacturing Practices. The targets include envelopes for VSV-G, GALV, RD114, and viral sequences such as Adenoviral E1a and the SV40 virus T antigen. This testing has been used for monitoring patients treated with gene therapy for evidence of recombinant viruses. Samples are tested at no cost to the investigator.
Vector copy number is also available for detecting vector within cell populations. The method uses droplet digital PCR and provide the vector copy number per cell. If you are interested in this service:
If you have any questions feel free to contact the NGVB Biorepository Manager:
Lorraine Matheson
317-274-4519
